Non-iterative methods for image improvement in digital holography of the retina

From LRDE

Abstract

With the increase of the number of people with moderate to severe visual impairment, monitoring and treatment of vision disorders have become major issues in medicine today. At the Quinze-Vingts national ophthalmology hospital in Paris, two optical benches have been settled in recent years to develop two real-time digital holography techniques for the retina: holographic optical coherence tomography (OCT) and laser Doppler holography. The first reconstructs three-dimensional images, while the second allows visualization of blood flow in vessels. Besides problems inherent to the imaging system itself, optical devices are subject to external disturbance, bringing also difficulties in imaging and loss of accuracy. The main obstacles these technologies face are eye motion and eye aberrations. In this thesis, we have introduced several methods for image quality improvement in digital holography, and validated them experimentally. The resolution of holographic images has been improved by robust non-iterative methods: lateral and axial tracking and compensation of translation movements, and measurement and compensation of optical aberrations. This allows us to be optimistic that structures on holographic images of the retina will be more visible and sharper, which could ultimately provide very valuable information to clinicians.

Documents

Bibtex (lrde.bib)

@PhDThesis{	  rivet.20.phd,
  author	= {Julie Rivet},
  title		= {Non-iterative methods for image improvement in digital
		  holography of the retina},
  school	= {Sorbonne Universit\'e},
  year		= 2020,
  address	= {Paris, France},
  month		= jul,
  abstract	= {With the increase of the number of people with moderate to
		  severe visual impairment, monitoring and treatment of
		  vision disorders have become major issues in medicine
		  today. At the Quinze-Vingts national ophthalmology hospital
		  in Paris, two optical benches have been settled in recent
		  years to develop two real-time digital holography
		  techniques for the retina: holographic optical coherence
		  tomography (OCT) and laser Doppler holography. The first
		  reconstructs three-dimensional images, while the second
		  allows visualization of blood flow in vessels. Besides
		  problems inherent to the imaging system itself, optical
		  devices are subject to external disturbance, bringing also
		  difficulties in imaging and loss of accuracy. The main
		  obstacles these technologies face are eye motion and eye
		  aberrations. In this thesis, we have introduced several
		  methods for image quality improvement in digital
		  holography, and validated them experimentally. The
		  resolution of holographic images has been improved by
		  robust non-iterative methods: lateral and axial tracking
		  and compensation of translation movements, and measurement
		  and compensation of optical aberrations. This allows us to
		  be optimistic that structures on holographic images of the
		  retina will be more visible and sharper, which could
		  ultimately provide very valuable information to
		  clinicians.}
}